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1

Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins

Pirazzini, Marco, Azarnia Tehran, Domenico, Zanetti, Giulia, Megighian, Aram, Scorzeto, Michele, Fillo, Silvia, Shone, Clifford C., Binz, Thomas, Rossetto, Ornella, Lista, Florigio, Montecucco, Cesare

Journal:

Year:

2014

Language:

english

File:

PDF, 2.28 MB

english, 2014

2

172. Effects of a syntaxin-specific botulinum neurotoxin type C on mice

Rossetto, Ornella, Zanetti, Giulia, Pirazzini, Marco, Tehran, Domenico Azarnia, Megighian, Aram, Henke, Tina, Binz, Thomas, Montecucco, Cesare

Journal:

Year:

2015

Language:

english

File:

PDF, 194 KB

english, 2015

3

On the Translocation of Botulinum and Tetanus Neurotoxins across the Membrane of Acidic Intracellular Compartments

Pirazzini, Marco, Tehran, Domenico Azarnia, Leka, Oneda, Zanetti, Giulia, Rossetto, Ornella, Montecucco, Cesare

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2015

Language:

english

File:

PDF, 604 KB

english, 2015

4

Genomic characterization of Italian Clostridium botulinum group I strains

Giordani, Francesco, Fillo, Silvia, Anselmo, Anna, Palozzi, Anna Maria, Fortunato, Antonella, Gentile, Bernardina, Azarnia Tehran, Domenico, Ciammaruconi, Andrea, Spagnolo, Ferdinando, Pittiglio, Vale

Journal:

Infection, Genetics and Evolution

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

5

The thioredoxin reductase – Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles

Pirazzini, Marco, Tehran, Domenico Azarnia, Zanetti, Giulia, Lista, Florigio, Binz, Thomas, Shone, Clifford C., Rossetto, Ornella, Montecucco, Cesare

Journal:

Year:

2015

Language:

english

File:

PDF, 563 KB

english, 2015

6

Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism

Zanetti, Giulia, Azarnia Tehran, Domenico, Pirazzini, Marcon, Binz, Thomas, Shone, Clifford C., Fillo, Silvia, Lista, Florigio, Rossetto, Ornella, Montecucco, Cesare

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.34 MB

english, 2015

7

188. EGA prevents the neuronal toxicity of BoNT/A and BoNT/B

Tehran, Domenico Azarnia, Mattarei, Andrea, Pirazzini, Marco, Zanetti, Giulia, Binz, Thomas, Shone, Clifford C., Rossetto, Ornella, Montecucco, Cesare

Journal:

Year:

2015

Language:

english

File:

PDF, 145 KB

english, 2015

8

160. Thioredoxin and its reductase are present on synaptic vesicles and their inhibition prevents the paralysis induced by botulinum neurotoxins

Pirazzini, Marco, Tehran, Domenico Azarnia, Zanetti, Giulia, Megighian, Aram, Rossetto, Ornella, Shone, Clifford, Binz, Thomas, Lista, Florigio, Montecucco, Cesare

Journal:

Year:

2015

Language:

english

File:

PDF, 57 KB

english, 2015

9

Hsp90 is involved in the entry of Clostridial Neurotoxins into the Cytosol of Nerve Terminals

Azarnia Tehran, Domenico, Pirazzini, Marco, Leka, Oneda, Mattarei, Andrea, Lista, Florigio, Binz, Thomas, Rossetto, Ornella, Montecucco, Cesare

Journal:

Cellular Microbiology

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

10

Erratum to “Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism” [Biochem. Pharmacol. 98 (2015) 522–530]

Zanetti, Giulia, Azarnia Tehran, Domenico, Pirazzini, Marco, Binz, Thomas, Shone, Clifford C., Fillo, Silvia, Lista, Florigio, Rossetto, Ornella, Montecucco, Cesare

Journal:

Biochemical Pharmacology

Year:

2016

Language:

english

File:

PDF, 160 KB

english, 2016

11

The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain

Zornetta, Irene, Azarnia Tehran, Domenico, Arrigoni, Giorgio, Anniballi, Fabrizio, Bano, Luca, Leka, Oneda, Zanotti, Giuseppe, Binz, Thomas, Montecucco, Cesare

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 889 KB

english, 2016

12

Multiple-locus variable number of tandem repeat analysis as a tool for molecular epidemiology of botulism: The Italian experience

Anniballi, Fabrizio, Fillo, Silvia, Giordani, Francesco, Auricchio, Bruna, Tehran, Domenico Azarnia, di Stefano, Enrica, Mandarino, Giuseppina, De Medici, Dario, Lista, Florigio

Journal:

Infection, Genetics and Evolution

Year:

2016

Language:

english

File:

PDF, 258 KB

english, 2016

13

A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins

Azarnia Tehran, Domenico, Zanetti, Giulia, Leka, Oneda, Lista, Florigio, Fillo, Silvia, Binz, Thomas, Shone, Clifford C., Rossetto, Ornella, Montecucco, Cesare, Paradisi, Cristina, Mattarei, Andrea, P

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.58 MB

english, 2015

14

A Weissella oryzae botulinum-like toxin cleaves vamp within the juxtamembrane domain

Montecucco, Cesare, Tehran, Domenico Azarnia, Zornetta, Irene, Arrigoni, Giorgio, Anniballi, Fabrizio, Bano, Luca, Leka, Oneda, Zanotti, Giuseppe, Binz, Thomas

Journal:

Year:

2016

Language:

english

File:

PDF, 242 KB

english, 2016

15

Hsp90, thioredoxin, and thioredoxin reductase form a chaperone-redox machinery enabling the catalytic activity of clostridial neurotoxins inside nerve terminals

Pirazzini, Marco, Tehran, Domenico Azarnia, Zanetti, Giulia, Leka, Oneda, Binz, Thomas, Lista, Florigio, Mattarei, Andrea, Rossetto, Ornella, Montecucco, Cesare

Journal:

Year:

2016

Language:

english

File:

PDF, 54 KB

english, 2016

16

Hsp90 and Thioredoxin-Thioredoxin Reductase enable the catalytic activity of Clostridial neurotoxins inside nerve terminals

Pirazzini, Marco, Azarnia Tehran, Domenico, Zanetti, Giulia, Rossetto, Ornella, Montecucco, Cesare

Journal:

Year:

2017

Language:

english

File:

PDF, 679 KB

english, 2017

17

Presynaptic endocytic factors in autophagy and neurodegeneration

Azarnia Tehran, Domenico, Kuijpers, Marijn, Haucke, Volker

Journal:

Current Opinion in Neurobiology

Year:

2018

Language:

english

File:

PDF, 661 KB

english, 2018

18

Novel Botulinum Neurotoxins: Exploring Underneath the Iceberg Tip

Tehran, Domenico, Pirazzini, Marco

Journal:

Year:

2018

Language:

english

File:

PDF, 829 KB

english, 2018

19

EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin

Schnell, Leonie, Mittler, Ann-Katrin, Sadi, Mirko, Popoff, Michel, Schwan, Carsten, Aktories, Klaus, Mattarei, Andrea, Tehran, Domenico, Montecucco, Cesare, Barth, Holger

Journal:

Year:

2016

Language:

english

File:

PDF, 3.64 MB

english, 2016

20

Semicarbazone EGA Inhibits Uptake of Diphtheria Toxin into Human Cells and Protects Cells from Intoxication

Schnell, Leonie, Mittler, Ann-Katrin, Mattarei, Andrea, Tehran, Domenico, Montecucco, Cesare, Barth, Holger

Journal:

Year:

2016

Language:

english

File:

PDF, 2.09 MB

english, 2016